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When the mysterious death of a 23-year-old mother in New Mexico goes unsolved, her family searches for answers.

When a millionaire is found dead in the trunk of her car, authorities become suspicious of her ex-husband.

When a woman disappears after an encounter on a train, her family hires detectives to investigate.

A woman claims to have been abducted from her multimillion-dollar home, leaving more than 150 investigators to search for her.

Michael Peterson, who was granted a new trial after the 2003 conviction in the murder of his wife was overturned, discusses the case and his decision to enter an Alford plea.

When detectives track down the killer of a Las Vegas cocktail waitress and mother, it becomes clear that the investigation has just begun.

When a San Diego woman who is near death arrives at an emergency room, the FBI and local law enforcement are called in to try to solve a medical mystery and a horrific crime.

Ohio investigators search for answers in the decades-old murder of 10-year-old Amy Mihaljevic; a retracing of Amy's steps from the day of the kidnapping.

A professional poker player's gamble may have resulted in a murder.

When a woman disappears after an encounter on a train, her family hires detectives to investigate.

A woman claims to have been abducted from her multimillion-dollar home, leaving more than 150 investigators to search for her.

Michael Peterson, who was granted a new trial after the 2003 conviction in the murder of his wife was overturned, discusses the case and his decision to enter an Alford plea.

When detectives track down the killer of a Las Vegas cocktail waitress and mother, it becomes clear that the investigation has just begun.

When a San Diego woman who is near death arrives at an emergency room, the FBI and local law enforcement are called in to try to solve a medical mystery and a horrific crime.

Ohio investigators search for answers in the decades-old murder of 10-year-old Amy Mihaljevic; a retracing of Amy's steps from the day of the kidnapping.

A professional poker player's gamble may have resulted in a murder.

The death of a mother of five tests a family's loyalty.

Rachel Buffett, whose former fiancé, Daniel Wozniak, was convicted of two grisly murders, talks about being at the center of the investigation.

The life of the charming con man who went by the name Clark Rockefeller.

Investigating the murder of a brilliant professor.

A daughter finds her father, a former FBI agent, murdered at his house; police dig into the man's past and begin to think the key to the mystery might be quite close to home.