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When a young, handsome veterinarian is found dead in his home in Montana, the mystery remains unsolved for nearly two decades.

A couple is murdered shortly after their wedding and police suspect a family feud is the cause; Josh Mankiewicz looks back at what started the dispute that left him floored.

A similar abduction in New Mexico helps crack the case of a 19-year-old missing college student in Oregon.

Through new interviews with insiders, take a look into Manson's world; learn how a career-criminal convinced his followers to kill innocent victims and deliver him the fame he craved.

A woman seeks the truth when her whirlwind romance turns into a mystery with government agents, cryptic messages and international spies.

A cold-case investigator helps police determine what happened to a missing woman.

On a family hunting trip in Newfoundland, a man is shot to death.

The missing-persons case of 12-year-old Jonelle Matthews in Colorado remained a mystery for more than three decades until detectives narrowed in on a suspect whose bizarre behavior after her disappearance hinted at something much more sinister.

After the cause of the death of Stacy Feldman in her Denver home is ruled as undetermined, friends and family join forces to piece together what happened; insiders close to the case speak out about the seven-year battle for justice.

A family begins a relentless pursuit of justice after the death of Nevada attorney Susan Winters is ruled a suicide; Susan's parents open up about the seven-year case and their efforts to push back against the criminal justice system.

When a young woman is found dead near a soccer field in Indiana, detectives try to piece together a puzzle that leads them to an unexpected suspect.

A young Tennessee woman mysteriously vanishes and misses her family's Thanksgiving dinner; determined to track her down, her family takes matters into their own hands, pursuing every digital clue she left behind.

Police suspect a serial killer when two women and their teenage daughters are murdered in Maryland; during the search for clues, it's revealed that a master thief is the key to solving the mystery.

When a young woman finds out that her boyfriend might have shot and killed a college football player out of revenge, she struggles with coming forward to officials, fearing she could lose her life.

Twenty-seven-year-old Egypt Covington is found murdered in her home; investigators in Michigan quickly identify a person of interest, but years pass without an arrest.

The investigation into a deadly home invasion involving a local business owner takes a turn when an unlikely witness comes forward; new details emerge from exclusive interviews and never-before-seen police interviews.

After a plastic surgeon and local musician is murdered in his Asheville, N.C., home, investigators uncover a trail of clues pointing to an unlikely killer; new details emerge from exclusive TV interviews with insiders close to the case.

A murder case considered closed by North Dakota detectives is suddenly reopened when a confidential informant comes forward with a tip about an unlikely suspect.

A woman finds herself on the wrong side of the law after she accuses her boyfriend of rape.

The FBI gets involved when a Virginia man's wife and son are kidnapped while vacationing in the Philippines, with a terrorist group demanding millions in ransom.

The Valseca siblings' lives are changed when their father is taken hostage in an orchestrated abduction.